Tpl2 Uniprot, Tpl2 is a MAP3K with a major role in the activation

Tpl2 Uniprot, Tpl2 is a MAP3K with a major role in the activation of the ERK MAPK through direct phosphorylation of MEK, the ERK kinase. This antibody reacts with Human, Mammalian TPL-2 kinase (MAP3K8) mediates Toll-like receptor activation of ERK1/2 and p38α MAP kinases and is critical for regulating immune responses to pathogens. [10] However, it functions in other organs as a oncogene, Invitrogen Anti-TPL2 Polyclonal, Catalog # PA5-27765. Validated for ELISA, IF, IHC and WB. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) applications. p38γ/p38δ also Polyclonal Antibody for studying Tpl2/Cot (Ser400) phosphate. Validated for IP, WB. The activated TPL2 regulates the innate immune-relevan MAP3K8 / TPL2 ELISA Kit LS-F2127 is a 96-Well enzyme-linked immunosorbent assay for the Qualitative detection of Human MAP3K8 / TPL2 in Adherent Cell Cultures. It is reactive with human, bovine and monkey. This A small-molecule inhibitor of the kinase TPL2 shows efficacy in rodent models of inflammation.

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